Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825835 | 0.80 | ABHD6 (0.37) | HDAC11ESR1ESR2DRD2MGLL | |
| SCHEMBL25825836 | 0.77 | ESR1 (0.36) | HDAC11ESR1ESR2 | |
| SCHEMBL25825897 | 0.75 | ABHD6 (0.47) | ESR1ESR2BCL2L1BADABHD6 | |
| SCHEMBL506963 | 0.72 | ESR1 (0.50) | ESR1ESR2DRD2DRD1BCL2L1 | |
| SCHEMBL8177222 | 0.71 | ESR1 (0.56) | ESR1ESR2BCL2L1BADABHD6 | |
| SCHEMBL25604192 | 0.71 | ESR1 (0.56) | ESR1ESR2DRD2DRD1BCL2L1 | |
| SCHEMBL19582436 | 0.69 | ESR1 (0.50) | ESR1ESR2DRD2DRD1BCL2L1 | |
| SCHEMBL25825832 | 0.68 | SIGMAR1 (0.46) | HDAC11 | |
| SCHEMBL11704797 | 0.67 | BCL2L1 (0.46) | DRD2DRD1BCL2L1BADHTR1A | |
| SCHEMBL25825833 | 0.67 | BCL2L1 (0.41) | DRD2DRD1BCL2L1BADHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |