Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 5/20 | 0.35 |
| ▸ | JAK1 | P23458 | 5/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825841 | 0.89 | L3MBTL1 (0.37) | SMN1; SMN2SCD5CYP11B2JAK2JAK1 | |
| SCHEMBL25825901 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2SCD5GPR119MAPTNR1H2 | |
| SCHEMBL25604354 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2SCD5JAK2JAK1GPR119 | |
| SCHEMBL25604198 | 0.80 | ESR2 (0.46) | SMN1; SMN2MAPTNR1H2 | |
| SCHEMBL25604262 | 0.80 | ESR2 (0.46) | SMN1; SMN2PARP1MAPTNR1H2 | |
| SCHEMBL25825842 | 0.75 | DDB1 (0.49) | SCD5GPR119 | |
| SCHEMBL25825902 | 0.72 | L3MBTL1 (0.39) | SMN1; SMN2GPR119NR1H2 | |
| SCHEMBL25604506 | 0.69 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPT | |
| SCHEMBL25825837 | 0.69 | ESR2 (0.40) | SCD5CYP11B2JAK2JAK1GPR119 | |
| SCHEMBL25604141 | 0.69 | MAPT (0.46) | SMN1; SMN2SCD5MAPTNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |