Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569124 | 0.81 | ENPP3 (0.42) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL2208059 | 0.81 | ENPP3 (0.42) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL4569141 | 0.81 | ENPP3 (0.42) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL18706862 | 0.81 | ENPP3 (0.42) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL5222510 | 0.79 | CYP2D6 (0.55) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL5222514 | 0.79 | CYP2D6 (0.55) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL12810140 | 0.79 | CYP2D6 (0.55) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL2632637 | 0.79 | CYP2D6 (0.55) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL5222520 | 0.79 | CYP2D6 (0.55) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR | |
| SCHEMBL79261 | 0.79 | ALDH1A1 (0.46) | CYP2D6CYP1A2ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CYP2D6 3632/4885CYP1A2 2835/4885ALDH1A1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.