Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27421364 | 0.87 | L3MBTL1 (0.40) | SMN1; SMN2MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL25826617 | 0.85 | FFAR1 (0.35) | SMN1; SMN2MEN1KMT2AL3MBTL1ROCK2 | |
| SCHEMBL25827944 | 0.83 | HRH3 (0.36) | SMN1; SMN2LMNAROCK2MAPT | |
| SCHEMBL25826613 | 0.79 | ESR1 (0.37) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL27102419 | 0.77 | MEN1 (0.42) | SMN1; SMN2MEN1KMT2AL3MBTL1ROCK2 | |
| SCHEMBL21120303 | 0.76 | KMT2A (0.43) | SMN1; SMN2MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL27305897 | 0.73 | ELANE (0.52) | SMN1; SMN2MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL25826624 | 0.73 | MEN1 (0.39) | SMN1; SMN2MEN1KMT2AL3MBTL1ROCK2 | |
| SCHEMBL18792766 | 0.72 | ELANE (0.46) | SMN1; SMN2MEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL25993800 | 0.72 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2AL3MBTL1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-11701427-B2 | Diels-alder conjugation methods | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | GLUL, TGM2, GLS | SMN1; SMN2 2409/4885MEN1 613/4885KMT2A 1013/4885 |
| US-11701427-B2 | Diels-alder conjugation methods | GLUL, TGM2, GLS | SMN1; SMN2 2409/4885MEN1 613/4885KMT2A 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.