Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27102419 | 0.82 | MEN1 (0.42) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL21120303 | 0.81 | KMT2A (0.43) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL25827949 | 0.81 | ELANE (0.40) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL25826617 | 0.80 | FFAR1 (0.35) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL10028025 | 0.80 | RAB9A (0.57) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL27305897 | 0.78 | ELANE (0.52) | MEN1KMT2ASMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL18792766 | 0.77 | ELANE (0.46) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL27421364 | 0.77 | L3MBTL1 (0.40) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL24541057 | 0.76 | MEN1 (0.43) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL12157064 | 0.76 | KMT2A (0.43) | MEN1KMT2AROCK2SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-11701427-B2 | Diels-alder conjugation methods | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207412-A1 | DIELS-ALDER CONJUGATION METHODS | GLUL, TGM2, GLS | MEN1 613/4885KMT2A 1013/4885ROCK2 3065/4885 |
| US-11701427-B2 | Diels-alder conjugation methods | GLUL, TGM2, GLS | MEN1 613/4885KMT2A 1013/4885ROCK2 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.