Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 6/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.45 |
| ▸ | CYBB | P04839 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25827046 | 0.87 | CYP3A4 (0.55) | GABRA5GRIN1GRIN2BCYP3A4 | |
| SCHEMBL25827018 | 0.82 | HPGD (0.57) | KMT2AMEN1CYP3A4 | |
| SCHEMBL1944562 | 0.75 | GRIN1 (0.49) | GABRA5GABRA1PKMKMT2AOPRM1 | |
| SCHEMBL31213524 | 0.74 | HPGD (0.51) | KMT2AMEN1CYP3A4 | |
| SCHEMBL3419641 | 0.73 | PKM (0.58) | GABRA5GABRA1PKMKMT2AOPRM1 | |
| SCHEMBL31213513 | 0.72 | HPGD (0.52) | KMT2AMEN1CYP3A4 | |
| SCHEMBL10254277 | 0.72 | MAPT (0.47) | GABRA5GABRA1PKMKMT2AMEN1 | |
| SCHEMBL4376936 | 0.71 | LMNA (0.52) | GABRA5GABRA1PKMSRCGRIN1 | |
| SCHEMBL320830 | 0.71 | RGS4 (0.53) | KMT2AMEN1 | |
| SCHEMBL10254821 | 0.71 | MAPT (0.49) | GABRA5GABRA1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |