Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 15/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 15/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25827237 | 0.87 | GABRA5 (0.48) | CYP3A4GRIN1GRIN2BGABRA5 | |
| SCHEMBL25827062 | 0.84 | CYP3A4 (0.69) | CYP3A4 | |
| SCHEMBL19485375 | 0.78 | CYP3A4 (0.53) | CYP3A4PARG | |
| SCHEMBL27383556 | 0.78 | CYP3A4 (0.54) | CYP3A4PARG | |
| SCHEMBL27385988 | 0.77 | CYP3A4 (0.52) | CYP3A4HIF1APARG | |
| SCHEMBL11223477 | 0.76 | GABRA1 (0.58) | GRIN1GRIN2BPARGGABRA5 | |
| SCHEMBL28411396 | 0.74 | CLPP (0.53) | CYP3A4GRIN1GRIN2BPARG | |
| SCHEMBL4847620 | 0.73 | ALDH1A1 (0.50) | CYP3A4PARG | |
| SCHEMBL28405041 | 0.72 | CYP3A4 (0.47) | CYP3A4PARG | |
| SCHEMBL6517583 | 0.72 | PARG (0.58) | GRIN1GRIN2BHIF1APARGGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |