SCHEMBL25827474

SCHEMBL25827474

C1=CC(c2nc(-c3ccccc3)nc(-c3cc(-c4cccc5cccc(-c6cc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)cc(C7CCCCC7)c6)c45)cc(C4CCCCC4)c3)n2)=CCC1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMO O15229 1/20 0.32
ADORA3 P0DMS8 2/20 0.32
ADORA2A P29274 2/20 0.32
ADORA1 P30542 2/20 0.32
POLB P06746 1/20 0.31
CASP3 P42574 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR5 Q9H228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25823003 0.87 L3MBTL1 (0.44) TDP1L3MBTL1KMOADORA3ADORA2A
SCHEMBL19622709 0.78 MAPT (0.41) TDP1L3MBTL1
SCHEMBL25823054 0.77 S1PR1 (0.44) TDP1L3MBTL1KMOADORA3ADORA2A
SCHEMBL26360651 0.76 MEN1 (0.35) L3MBTL1KMOADORA3ADORA2AADORA1
SCHEMBL27250153 0.76 GPR55 (0.34) L3MBTL1ADORA3ADORA2AADORA1
SCHEMBL23959647 0.75 L3MBTL1 (0.53) TDP1L3MBTL1KMOADORA3ADORA2A
SCHEMBL25822998 0.75 L3MBTL1 (0.53) TDP1L3MBTL1KMOADORA3ADORA2A
SCHEMBL23959648 0.75 L3MBTL1 (0.53) TDP1L3MBTL1KMOADORA3ADORA2A
SCHEMBL23959741 0.74 TDP1 (0.49) TDP1L3MBTL1KMOADORA3ADORA2A
SCHEMBL13262321 0.73 L3MBTL1 (0.44) L3MBTL1ADORA3ADORA2AADORA1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225202-A1 CYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225202-A1 CYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, CRY2, PER2 TDP1 3027/4885L3MBTL1 1424/4885KMO 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.