SCHEMBL25827483

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25827482	0.89	ALDH1A1 (0.46)	GPR55MAPTSMN1; SMN2MEN1KMT2A
	SCHEMBL25252926	0.83	MAPT (0.59)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL1834668	0.79	GPR55 (0.46)	GPR55MAPTSMN1; SMN2POLBMEN1
	SCHEMBL26192797	0.78	KDM4E (0.46)	MAPTSMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL19086906	0.75	L3MBTL1 (0.67)	MAPTPOLBMEN1KMT2ALMNA
	SCHEMBL31128117	0.72	ALDH1A1 (0.52)	MAPTSMN1; SMN2LMNAHTTKDM4E
	SCHEMBL18996860	0.72	ALDH1A1 (0.46)	MAPTSMN1; SMN2POLBLMNAKDM4E
	SCHEMBL30376503	0.71	ALDH1A1 (0.55)	MAPTSMN1; SMN2POLBMEN1KMT2A
	SCHEMBL24214370	0.71	ALDH1A1 (0.55)	MAPTSMN1; SMN2POLBMEN1KMT2A
	SCHEMBL25828126	0.71	MEN1 (0.42)	MAPTSMN1; SMN2POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.