Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26721599 | 0.90 | OPRL1 (0.42) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL3422430 | 0.86 | CYP2C9 (0.47) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL3420466 | 0.86 | CYP2C9 (0.47) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL25827593 | 0.83 | CYP2C9 (0.44) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL17835297 | 0.78 | ALDH1A1 (0.43) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL5448789 | 0.77 | ALDH1A1 (0.46) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL3420479 | 0.76 | MAPT (0.40) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL9749352 | 0.75 | KMT2A (0.43) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL5440979 | 0.75 | ALDH1A1 (0.42) | OPRL1ALDH1A1TSHRLMNACYP2C9 | |
| SCHEMBL11279187 | 0.74 | PDE7A (0.45) | OPRL1ALDH1A1TSHRLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-12-01 | — | — | US | disclosed |
| US-4202975-A | ANTIINFLAMMATORY ANALGESIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-05-13 | — | — | US | disclosed |
| US-4129654-A | Isoxazolo[3,4-d]pyrimidines useful as antiinflammatory-analgesic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | OPRL1 3901/4885ALDH1A1 83/4885TSHR 4878/4885 |
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | KRT18, CKAP4, KRTCAP2 | OPRL1 3764/4885ALDH1A1 240/4885TSHR 4820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.