SCHEMBL25828198

SCHEMBL25828198

CCCCC(O)(CC)C(=O)c1ccc(CC(C(=O)N(CCO)CCO)C(=O)N(CCO)CCO)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 7/20 0.37
THRB P10828 7/20 0.37
MLYCD O95822 1/20 0.33
BDKRB2 P30411 1/20 0.32
RARB P10826 2/20 0.32
PLK1 P53350 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
HAO1 Q9UJM8 1/20 0.31
TNNC1 P63316 2/20 0.30
SGPL1 O95470 1/20 0.30
S1PR4 O95977 1/20 0.30
S1PR1 P21453 1/20 0.30
GPR183 P32249 1/20 0.30
CERS2 Q96G23 1/20 0.30
S1PR3 Q99500 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25828196 0.80 MLYCD (0.33) THRATHRBMLYCDHDAC3HDAC1
SCHEMBL10710059 0.75 THRA (0.54) THRATHRBRARBHAO1TNNC1
SCHEMBL6699980 0.72 CA2 (0.46) MLYCD
SCHEMBL10384783 0.71 HDAC1 (0.48) HDAC3HDAC1HDAC2HDAC6
SCHEMBL4415992 0.71 MLYCD (0.35) MLYCDBDKRB2HDAC6
SCHEMBL6702050 0.71 USP5 (0.41) MLYCD
SCHEMBL6696379 0.70 HDAC3 (0.45) HDAC3HDAC1HDAC2
SCHEMBL10384322 0.70 HTR7 (0.51) MLYCDHDAC3HDAC1HDAC2
SCHEMBL6692640 0.70 GAA (0.48)
SCHEMBL25848368 0.70 MDM2 (0.46) HDAC3HDAC1HDAC2HDAC6NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023180075-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-28 WO disclosed
EP-4249518-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-27 EP disclosed
WO-2023126223-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-06 WO disclosed
EP-4206183-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-05 EP disclosed