SCHEMBL25848368

SCHEMBL25848368

O=C(c1ccccc1)c1ccc(CC(C(=O)N(CCO)CCO)C(=O)N(CCO)CCO)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.46
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
GLI1 P08151 2/20 0.43
GLI2 P10070 2/20 0.43
GAA P10253 1/20 0.42
ACHE P22303 1/20 0.41
HDAC3 O15379 3/20 0.41
HDAC4 P56524 3/20 0.41
HDAC1 Q13547 3/20 0.41
HDAC2 Q92769 3/20 0.41
HDAC10 Q969S8 3/20 0.41
HDAC8 Q9BY41 3/20 0.41
HDAC6 Q9UBN7 3/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC9 Q9UKV0 2/20 0.41
HDAC5 Q9UQL6 2/20 0.41
SRD5A2 P31213 2/20 0.41
PPARG P37231 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25828105 0.81 GLI1 (0.41) MDM2ALDH1A1HPGDGLI1GLI2
SCHEMBL15391739 0.79 MDM2 (0.60) MDM2ALDH1A1HPGDSRD5A2PPARG
SCHEMBL25828196 0.77 MLYCD (0.33) MDM2HDAC3HDAC4HDAC1HDAC2
SCHEMBL3091602 0.74 MDM2 (0.55) MDM2ALDH1A1HPGDGAASRD5A2
SCHEMBL15391136 0.74 MDM2 (0.55) MDM2ALDH1A1HPGDSRD5A2PPARG
SCHEMBL4543370 0.73 ACHE (0.63) ALDH1A1HPGDGAAACHEHDAC3
SCHEMBL25828197 0.73 MC4R (0.32) HDAC3HDAC4HDAC1HDAC2HDAC10
SCHEMBL27233078 0.72 ACHE (0.51) ALDH1A1HPGDGLI1GLI2GAA
Benzophenone SCHEMBL9545189 0.71 ALDH1A1 (0.61) ALDH1A1HPGDGAAACHESRD5A2
SCHEMBL27696374 0.71 ALDH1A1 (0.50) MDM2ALDH1A1HPGDGAASRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023180075-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-28 WO disclosed
EP-4249518-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-27 EP disclosed
EP-4206183-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-05 EP disclosed