Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18310647 | 0.89 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL25827151 | 0.81 | — | — | |
| SCHEMBL18310674 | 0.77 | PNMT (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL23481727 | 0.71 | — | — | |
| SCHEMBL25196687 | 0.68 | ATM (0.30) | — | |
| SCHEMBL25828856 | 0.67 | EIF4A3 (0.38) | — | |
| SCHEMBL22763888 | 0.66 | GABRA1 (0.31) | — | |
| SCHEMBL13747960 | 0.66 | GABRA1 (0.41) | — | |
| SCHEMBL12295184 | 0.65 | MET (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL18882777 | 0.65 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125841-A1 | HETEROCYCLIC COMPOUND AS POLθ INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-07-06 | — | — | WO | disclosed |