SCHEMBL258295

SCHEMBL258295

CCc1cc2ccccc2[c]c1C

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP2A6 P11509 2/20 0.35
CYP1A2 P05177 1/20 0.35
ATM Q13315 1/20 0.35
MGLL Q99685 1/20 0.32
BRD4 O60885 1/20 0.32
GRM1 Q13255 2/20 0.31
RXFP1 Q9HBX9 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
GABRA1 P14867 2/20 0.30
GABRB2 P47870 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
TLR8 Q9NR97 1/20 0.30
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63968 0.82 KDM4E (0.41) MAPTKDM4EALDH1A1CYP2A6CYP1A2
SCHEMBL10822574 0.79 KDM4E (0.39) MAPTKDM4EALDH1A1CYP2A6CYP1A2
SCHEMBL7094679 0.79 KDM4E (0.39) MAPTKDM4EALDH1A1CYP2A6CYP1A2
SCHEMBL64492 0.75 BRD4 (0.39) ALDH1A1CYP2A6CYP1A2BRD4TDP1
SCHEMBL5748901 0.74 GABRA1 (0.36) MAPTKDM4EALDH1A1CYP2A6CYP1A2
SCHEMBL5747837 0.74 GABRA1 (0.36) MAPTKDM4EALDH1A1CYP2A6CYP1A2
SCHEMBL4802146 0.74 KDM4E (0.44) MAPTKDM4EALDH1A1CYP2A6CYP1A2
SCHEMBL76620 0.72 IDO1 (0.34) MAPTALDH1A1CYP2A6TDP1
SCHEMBL10822591 0.72 MAPT (0.35) MAPTALDH1A1CYP2A6CYP1A2TDP1
SCHEMBL3269198 0.72 ACHE (0.34) CYP2A6CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9404059-B2 Lubricating oil composition for machining tool JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-08-02 US disclosed
EP-1422287-B1 LUBRICATING OIL COMPOSITION FOR AUTOMATIC TRANSMISSION NIPPON OIL CORP (JP) 2016-02-17 EP disclosed
US-20150072908-A1 LUBRICATING OIL COMPOSITION FOR MACHINING TOOL JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-03-12 US disclosed
EP-2423297-B1 Hydraulic oil composition NIPPON OIL CORP (JP) 2013-06-05 EP disclosed
EP-1721957-B1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT NIPPON OIL CORP (JP) 2013-04-10 EP disclosed
US-8299006-B2 Compressor oil composition NIPPON OIL CORPORATION (JP) 2012-10-30 US disclosed
US-8247360-B2 Heat treating oil composition NIPPON OIL CORPORATION (JP) 2012-08-21 US disclosed
US-8240235-B2 Method of minimal quantity lubrication cutting/grinding processing and oil composition used therefor NIPPON OIL CORPORATION (JP) 2012-08-14 US disclosed
US-8236740-B2 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2012-08-07 US disclosed
US-8232233-B2 Lubricating oil composition for machine tools NIPPON OIL CORPORATION (JP) 2012-07-31 US disclosed
US-6432889-B1 MIXTURE CONTAINING OVERBASED COMPOUND; WEAR AND FRICTION RESISTANCE NIPPON MITSUBISHI OIL CORPORATION (JP) 2002-08-13 US disclosed
EP-0972821-A2 Grease composition suitable for a constant velocity joint Nippon Mitsubishi Oil Corporation (JP) 2000-01-19 EP disclosed
US-5912212-A OIL WITH 3-METHYL-5-TERT-BUTYL-4-HYDROXYPHENYL FATTY ESTER, SULFUR AND PHOSPHORUS NIPPON OIL CO., LTD. (JP) 1999-06-15 US disclosed
EP-0896050-A1 Lubricating oil composition comprising a specific base oil and an oxidation inhibitor NIPPON OIL CO., LTD. (JP) 1999-02-10 EP disclosed
US-5663125-A POLYETHERS, BORONATED AMINES NIPPON OIL CO., LTD. (JP) 1997-09-02 US disclosed
EP-0781834-A2 Lubricating oil composition NIPPON OIL CO. LTD. (JP) 1997-07-02 EP disclosed
US-5549838-A CONTAINING LUBRICATING OIL, PHOSPHORIC ACID ESTER OR PHOSPHOROUS ACID ESTER, ALKYLENE OXIDE ADDUCT OF ALIPHATIC MONOAMINE OR ALIPHATIC POLYAMINE OR SALT THEREOF WITH ALIPHATIC ACID, ALIPHATIC MONOAMINE NIPPON OIL CO., LTD. (JP) 1996-08-27 US disclosed
US-5536423-A Hydraulic working oil composition for buffers NIPPON OIL CO., LTD. (JP) 1996-07-16 US disclosed
EP-0636680-A1 LUBRICANT FOR A TWO CYCLE ENGINE Nippon Oil Co., Ltd. (JP) 1995-02-01 EP disclosed
EP-0593068-A1 Hydraulic working oil composition for buffers NIPPON OIL COMPANY, LIMITED (JP) 1994-04-20 EP disclosed