SCHEMBL25830003

SCHEMBL25830003

CC(=O)c1ccn(C(=O)N2CCN(Cc3ccc(Cl)cc3N3CC4COCC4C3)CC2)n1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.53
FAAH O00519 10/20 0.52
PLA2G7 Q13093 2/20 0.44
ABHD6 Q9BV23 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567696 0.92 FAAH (0.61) MGLLFAAH
SCHEMBL25829996 0.90 MGLL (0.54) MGLLFAAHPLA2G7ABHD6
SCHEMBL20503506 0.87 MGLL (0.46) MGLLFAAHPLA2G7ABHD6
SCHEMBL25829997 0.87 FAAH (0.66) MGLLFAAHPLA2G7ABHD6
SCHEMBL25829995 0.87 FAAH (0.48) MGLLFAAHABHD6
SCHEMBL25829981 0.84 FAAH (0.54) MGLLFAAHPLA2G7ABHD6
SCHEMBL25487891 0.83 MGLL (0.62) MGLLFAAHPLA2G7ABHD6
SCHEMBL25829880 0.82 FAAH (0.51) MGLLFAAHPLA2G7ABHD6
SCHEMBL25829884 0.81 MGLL (0.45) MGLLFAAH
SCHEMBL25830459 0.80 FAAH (0.66) MGLLFAAHPLA2G7ABHD6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219897-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219897-A1 PYRAZOLE MAGL INHIBITORS MGLL, PNLIP, LPL MGLL 1/4885FAAH 33/4885PLA2G7 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.