Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2583129 | 1.00 | MDM2 (0.34) | MDM2FFAR2HSD11B1SLC22A12 | |
| SCHEMBL2588032 | 0.87 | FFAR2 (0.38) | MDM2FFAR2 | |
| SCHEMBL2588033 | 0.87 | FFAR2 (0.38) | MDM2FFAR2 | |
| SCHEMBL2585734 | 0.82 | FFAR2 (0.34) | FFAR2 | |
| SCHEMBL2585730 | 0.82 | FFAR2 (0.34) | FFAR2 | |
| SCHEMBL4513172 | 0.82 | MDM2 (0.35) | MDM2FFAR2HSD11B1 | |
| SCHEMBL4513168 | 0.82 | MDM2 (0.35) | MDM2FFAR2HSD11B1 | |
| SCHEMBL2585819 | 0.81 | RIPK1 (0.40) | FFAR2 | |
| SCHEMBL2585817 | 0.81 | RIPK1 (0.40) | FFAR2 | |
| SCHEMBL2585660 | 0.80 | FFAR2 (0.35) | FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |