Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588033 | 1.00 | FFAR2 (0.38) | FFAR2RIPK1MAOAMAOBADAM17 | |
| SCHEMBL2585819 | 0.88 | RIPK1 (0.40) | FFAR2RIPK1MAOAMAOBPDE5A | |
| SCHEMBL2585817 | 0.88 | RIPK1 (0.40) | FFAR2RIPK1MAOAMAOBPDE5A | |
| SCHEMBL2583129 | 0.87 | MDM2 (0.34) | FFAR2MDM2 | |
| SCHEMBL2583133 | 0.87 | MDM2 (0.34) | FFAR2MDM2 | |
| SCHEMBL4502256 | 0.83 | FFAR2 (0.38) | FFAR2RIPK1ADAM17PDE5ACHRNA7 | |
| SCHEMBL4502251 | 0.83 | FFAR2 (0.38) | FFAR2RIPK1ADAM17PDE5ACHRNA7 | |
| SCHEMBL2585730 | 0.81 | FFAR2 (0.34) | FFAR2RIPK1 | |
| SCHEMBL2585734 | 0.81 | FFAR2 (0.34) | FFAR2RIPK1 | |
| SCHEMBL2588030 | 0.80 | FFAR2 (0.39) | FFAR2RIPK1TP53MDM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |