Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812369 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL31497500 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL611860 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHTTPOLB | |
| Hydrochloric Acid SCHEMBL29624968 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL25888932 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL25509745 | 0.84 | HTT (0.43) | ALDH1A1MEN1KMT2AHTTGAA | |
| SCHEMBL21960356 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL23563104 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL21963075 | 0.82 | MITF (0.49) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL21960987 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702428-B2 | Chemical compounds as inhibitors of interleukin-1 activity | GENENTECH, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702428-B2 | Chemical compounds as inhibitors of interleukin-1 activity | IL1B, IL1A, IL18 | ALDH1A1 649/4885MEN1 4064/4885KMT2A 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.