Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.79 |
| ▸ | BACE1 | P56817 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NSD2 | O96028 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 3/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28121286 | 0.83 | BACE1 (0.60) | PTPN1BACE1MEN1KMT2ANSD2 | |
| SCHEMBL11048150 | 0.81 | BACE1 (0.72) | PTPN1BACE1MEN1KMT2ANSD2 | |
| SCHEMBL5485068 | 0.80 | BACE1 (1.00) | PTPN1BACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29673492 | 0.80 | BACE1 (1.00) | PTPN1BACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29647664 | 0.79 | BACE1 (0.73) | PTPN1BACE1MEN1KMT2ACDC25B | |
| SCHEMBL27006528 | 0.79 | BACE1 (0.73) | PTPN1BACE1MEN1KMT2ACDC25B | |
| Methylamine SCHEMBL3277347 | 0.79 | BACE1 (0.89) | PTPN1BACE1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25834756 | 0.79 | BACE1 (0.75) | PTPN1BACE1MEN1KMT2ACDC25B | |
| SCHEMBL28556962 | 0.77 | BACE1 (0.72) | PTPN1BACE1MEN1KMT2ANSD2 | |
| SCHEMBL31423340 | 0.77 | BACE1 (1.00) | PTPN1BACE1MEN1KMT2ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
| CN-113861169-A | Polysubstituted naphtho-dihydrofuran compound, preparation method and application thereof | 西华大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-108530394-A | A kind of synthesis vitamin K3The method of epoxides | 中国科学院成都有机化学有限公司 | 2018-09-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | NFE2L2, DUOX1, DUOX2 | PTPN1 4633/4885BACE1 608/4885MEN1 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.