Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834704 | 1.00 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL25834375 | 0.89 | MAPT (0.45) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL25835377 | 0.81 | MAOA (0.46) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL16072720 | 0.78 | KCNA3 (0.58) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL9173435 | 0.76 | KCNA3 (0.56) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL9754264 | 0.75 | KCNA3 (0.63) | PTGER1PTGER4PTGER3PTGER2MAPT | |
| SCHEMBL8216313 | 0.75 | MAPT (0.69) | MAPTMAPK1TDP1L3MBTL1ALPG | |
| SCHEMBL5838519 | 0.74 | MAPT (0.50) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL30660808 | 0.74 | MAPT (0.50) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL25834309 | 0.74 | TOP1 (0.56) | PTGER1PTGER4PTGER3PTGER2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | NFE2L2, DUOX1, DUOX2 | PTGER1 3718/4885PTGER4 3572/4885PTGER3 3870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.