SCHEMBL25835398

SCHEMBL25835398

CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCCOCCNC(=O)CCOCCCl

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.67
ALDH1A1 P00352 3/20 0.67
HPGD P15428 3/20 0.67
MAPT P10636 2/20 0.67
ALOX12 P18054 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
FAAH O00519 1/20 0.67
CNR2 P34972 1/20 0.67
TRPV1 Q8NER1 1/20 0.63
MEN1 O00255 1/20 0.63
BLM P54132 1/20 0.63
KMT2A Q03164 1/20 0.63
KDM4E B2RXH2 1/20 0.60
ENPP2 Q13822 1/20 0.58
LPAR1 Q92633 1/20 0.58
LPAR2 Q9HBW0 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25835403 0.96 LPAR1 (0.62) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL25835554 0.89 FAAH (0.66) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL25835652 0.88 CNR1 (0.64) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL26032911 0.87 FAAH (0.64) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL25835512 0.86 FAAH (0.70) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL26032564 0.85 CNR1 (0.57) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL26032894 0.85 FAAH (0.68) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL25835638 0.83 LPAR1 (0.67) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL26032862 0.83 SLC6A5 (0.66) CNR1ALDH1A1HPGDMAPTALOX12
SCHEMBL4387701 0.82 CNR1 (0.68) CNR1ALDH1A1HPGDMAPTALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 CNR1 4510/4885ALDH1A1 1330/4885HPGD 2974/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 CNR1 4167/4885ALDH1A1 2528/4885HPGD 3988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.