SCHEMBL258368

SCHEMBL258368

CCCc1ncccc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALDH1A1 P00352 5/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
BLM P54132 1/20 0.52
AGER Q15109 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.50
NAPRT Q6XQN6 2/20 0.50
LMNA P02545 1/20 0.50
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MYC P01106 1/20 0.46
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
GABRA1 P14867 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5739430 0.98 KDM4E (0.52) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL4005286 0.90 GABRP (0.56) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL7386044 0.88 GABRP (0.51) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL5002869 0.87 GABRP (0.50) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL135492 0.87 GABRP (0.50) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL29398777 0.87 GABRP (0.50) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL9500202 0.87 GABRP (0.50) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL5002408 0.87 GABRP (0.50) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL4625244 0.87 GABRP (0.50) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4
SCHEMBL5709741 0.87 GABRP (0.50) KDM4ETDP1ALDH1A1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517880-B1 PRODUCTION OF CIS-PELLITORIN AND USE AS A FLAVOURING SYMRISE AG (DE) 2011-01-05 EP claimed
EP-1633334-B1 TOPICAL ADMINISTRATION OF VASOACTIVE VITAMIN B3 COMPOUNDS FOR PROMOTING SLEEP PROCTER & GAMBLE (US) 2006-11-15 EP claimed
EP-1335715-B1 SKIN-FRIENDLY AND DRUG-CONTAINING PATCHES FOR TRANSDERMAL ADMINISTRATION OF HYPEREMIC ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2005-05-11 EP claimed
EP-1335715-A2 SKIN FRIENDLY ACTIVE INGREDIENT PLASTER FOR TRANSDERMAL ADMINISTRATION OF RUBEFACIENT ACTIVE INGREDIENTS Beiersdorf AG (DE) 2003-08-20 EP claimed
EP-0846463-B1 Active substance containing plaster BEIERSDORF AG (DE) 2003-02-26 EP claimed
WO-2002038137-A2 SKIN FRIENDLY ACTIVE INGREDIENT PLASTER FOR TRANSDERMAL ADMINISTRATION OF RUBEFACIENT ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2002-05-16 WO claimed
EP-0846463-A2 Active substance containing plaster Beiersdorf Aktiengesellschaft (DE) 1998-06-10 EP claimed
WO-1992012699-A1 COSMETIC OR PHARMACEUTICAL COMPOSITIONS FOR IMPROVING HAIR QUALITY AND PROMOTING HAIR GROWTH WEUFFEN WOLFGANG (DE) 1992-08-06 WO claimed
EP-4699452-A2 OBTAINING A VOLATILE FRACTION FROM JUICES OR ALCOHOLIC BEVERAGES Symrise AG (DE) 2026-02-25 EP disclosed
US-20260041109-A1 ROBUST FLAVOR EMULSIONS INT FLAVORS & FRAGRANCES INC (US) 2026-02-12 US disclosed
EP-3836799-B1 OBTAINING A VOLATILE FRACTION FROM JUICES OR ALCOHOLIC BEVERAGES SYMRISE AG (DE) 2025-11-26 EP disclosed
US-12479827-B2 Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-11-25 US disclosed
US-12419815-B2 Microcapsule compositions stabilized with viscosity control agents INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US disclosed
EP-4615958-A1 CELL COMPOSITIONS Givaudan SA (CH) 2025-09-17 EP disclosed
US-5321001-A Photodynamic plant defoliants THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1994-06-14 US disclosed
US-5242892-A With 5-aminolevulinic acid THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1993-09-07 US disclosed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP disclosed
US-5163990-A Modulation of chlorophyll biosynthesis THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1992-11-17 US disclosed
WO-1992012699-A1 COSMETIC OR PHARMACEUTICAL COMPOSITIONS FOR IMPROVING HAIR QUALITY AND PROMOTING HAIR GROWTH WEUFFEN WOLFGANG (DE) 1992-08-06 WO disclosed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479827-B2 Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors KLKB1, KLK5, KLK1 KDM4E 331/4885TDP1 2205/4885ALDH1A1 1223/4885
US-12419815-B2 Microcapsule compositions stabilized with viscosity control agents ACR, ALG1, MLEC KDM4E 4393/4885TDP1 2010/4885ALDH1A1 4627/4885
US-20260041109-A1 ROBUST FLAVOR EMULSIONS ACACA, FABP4, CUTA KDM4E 4681/4885TDP1 2420/4885ALDH1A1 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.