SCHEMBL25837923

SCHEMBL25837923

CCOC(=O)c1ccc([N+](=O)[O-])cc1[18F]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.64
MAPT P10636 5/20 0.50
ALDH1A1 P00352 4/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 1/20 0.49
HPGD P15428 1/20 0.49
LMNA P02545 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
NPC1 O15118 1/20 0.49
CACNA1C Q13936 2/20 0.47
CACNA1F O60840 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CACNA1D Q01668 1/20 0.47
CACNA1S Q13698 1/20 0.47
AR P10275 2/20 0.47
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
ADRB3 P13945 1/20 0.46
MITF O75030 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2062103 1.00 SMN1; SMN2 (0.64) SMN1; SMN2MAPTALDH1A1KMT2AMEN1
SCHEMBL1496409 0.88 SMN1; SMN2 (0.60) SMN1; SMN2MAPTALDH1A1KMT2AMEN1
SCHEMBL7723906 0.86 SMN1; SMN2 (0.68) SMN1; SMN2MAPTALDH1A1KMT2AMEN1
SCHEMBL426382 0.85 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1KMT2AMEN1
SCHEMBL26870536 0.84 SMN1; SMN2 (0.49) SMN1; SMN2MAPTALDH1A1KMT2ATP53
SCHEMBL14567836 0.84 SMN1; SMN2 (0.49) SMN1; SMN2MAPTALDH1A1KMT2ALMNA
SCHEMBL30686809 0.84 SMN1; SMN2 (0.49) SMN1; SMN2MAPTALDH1A1KMT2ALMNA
SCHEMBL5925545 0.84 SMN1; SMN2 (0.65) SMN1; SMN2MAPTALDH1A1KMT2AMEN1
SCHEMBL6750268 0.84 SMN1; SMN2 (0.65) SMN1; SMN2MAPTALDH1A1KMT2AMEN1
SCHEMBL9080448 0.83 SMN1; SMN2 (0.55) SMN1; SMN2MAPTALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226228-A1 POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR DETECTION OF BACTERIAL INFECTION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226228-A1 POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR DETECTION OF BACTERIAL INFECTION TLR5, SLC10A2, FNTB SMN1; SMN2 3077/4885MAPT 778/4885ALDH1A1 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.