SCHEMBL26032070

SCHEMBL26032070

CCCCCCCCCCCCCCCC(=O)NCCOCCNC(=O)CC[C@H](NC(=O)CCOCCOCCNC(=O)CCN1C(=O)CC(C(C)C)C1=O)C(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.52
LPAR3 Q9UBY5 4/20 0.36
TLR2 O60603 2/20 0.36
OPRK1 P41145 2/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LPAR1 Q92633 2/20 0.36
NOD1 Q9Y239 2/20 0.35
SIRT2 Q8IXJ6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032037 1.00 GLP1R (0.52) GLP1RLPAR3TLR2OPRK1HPGD
SCHEMBL26032035 1.00 GLP1R (0.52) GLP1RLPAR3TLR2OPRK1HPGD
SCHEMBL26032052 0.95 GLP1R (0.48) GLP1ROPRK1LPAR1
SCHEMBL26032060 0.95 GLP1R (0.47) GLP1RLPAR1
SCHEMBL26032096 0.94 GLP1R (0.48) GLP1RLPAR3TLR2OPRK1SIRT2
SCHEMBL26032226 0.91 HPGD (0.43) GLP1RHPGDHTTSMN1; SMN2LPAR1
SCHEMBL26032046 0.91 GLP1R (0.44) GLP1RHPGD
SCHEMBL24589077 0.89 GLP1R (0.55) GLP1RTLR2OPRK1SIRT2
SCHEMBL26972994 0.88 GLP1R (0.46) GLP1RTLR2OPRK1NOD1SIRT2
SCHEMBL24589064 0.86 GLP1R (0.46) GLP1RTLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GLP1R 1683/4885LPAR3 1763/4885TLR2 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.