SCHEMBL26032096

SCHEMBL26032096

CCCCCCCCC(CCCCCC)C(=O)NCCOCCNC(=O)CC[C@H](NC(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)CC(C(C)C)C1=O)C(=O)NCCOCCNC(=O)C(CCCCCC)CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.48
OPRK1 P41145 2/20 0.36
BCHE P06276 3/20 0.34
ACHE P22303 3/20 0.34
SIRT2 Q8IXJ6 2/20 0.34
TLR2 O60603 2/20 0.34
LPAR3 Q9UBY5 2/20 0.33
CACNA1F O60840 1/20 0.33
CACNA1D Q01668 1/20 0.33
CACNA1S Q13698 1/20 0.33
CACNA1C Q13936 1/20 0.33
MMP1 P03956 1/20 0.33
MMP3 P08254 1/20 0.33
SIRT1 Q96EB6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032035 0.94 GLP1R (0.52) GLP1ROPRK1SIRT2TLR2LPAR3
SCHEMBL26032070 0.94 GLP1R (0.52) GLP1ROPRK1SIRT2TLR2LPAR3
SCHEMBL26032037 0.94 GLP1R (0.52) GLP1ROPRK1SIRT2TLR2LPAR3
SCHEMBL26032052 0.90 GLP1R (0.48) GLP1ROPRK1
SCHEMBL26032060 0.89 GLP1R (0.47) GLP1R
SCHEMBL26032100 0.86 CNR1 (0.35) GLP1ROPRK1
SCHEMBL26032046 0.86 GLP1R (0.44) GLP1R
SCHEMBL24589077 0.85 GLP1R (0.55) GLP1ROPRK1SIRT2TLR2SIRT1
SCHEMBL26032226 0.85 HPGD (0.43) GLP1R
SCHEMBL26972994 0.85 GLP1R (0.46) GLP1ROPRK1SIRT2TLR2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GLP1R 1683/4885OPRK1 1136/4885BCHE 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.