SCHEMBL25838447

SCHEMBL25838447

O=C(O)c1cc(O)c(-c2ccc([SH](c3ccccc3)c3ccccc3)cc2)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 9/20 0.49
MCL1 Q07820 4/20 0.49
HNF4A P41235 3/20 0.49
DHFR P00374 1/20 0.49
BACE1 P56817 1/20 0.47
PTPN1 P18031 1/20 0.42
GPR35 Q9HC97 1/20 0.41
THRB P10828 1/20 0.41
HSD17B10 Q99714 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
KDM4E B2RXH2 1/20 0.40
CA12 O43570 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
HMGB1 P09429 1/20 0.40
HPGD P15428 1/20 0.40
CA4 P22748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25724110 0.76 ACMSD (0.70) ACMSDMCL1HNF4ADHFRCA12
SCHEMBL25718037 0.76 ACMSD (0.71) ACMSDMCL1HNF4ADHFR
SCHEMBL25838444 0.73 ACMSD (0.47) ACMSDMCL1HNF4ADHFRPTPN1
SCHEMBL28054694 0.72 ALDH1A1 (0.50) ACMSDHNF4AHSD17B10AKR1C3KDM4E
SCHEMBL22088482 0.71 PRKAB2 (0.56) ACMSDMCL1HNF4ADHFRBACE1
SCHEMBL17384104 0.71 HNF4A (0.68) ACMSDHNF4APTPN1KDM4ECA12
SCHEMBL11086117 0.70 BACE1 (0.61) ACMSDMCL1HNF4ADHFRBACE1
SCHEMBL163610 0.70 CA1 (0.59) ACMSDMCL1HNF4ADHFRPTPN1
SCHEMBL2533617 0.69 ACMSD (0.76) ACMSDMCL1HNF4ADHFRPTPN1
SCHEMBL9249788 0.69 CYP2C8 (0.57) ACMSDMCL1HNF4ADHFRBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11693313-B2 Resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11693313-B2 Resist composition and method of forming resist pattern C1R, C1S, C9 ACMSD 2362/4885MCL1 2124/4885HNF4A 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.