Biphenyl

Biphenyl

SCHEMBL2583908

N#COc1ccc(OOOc2ccc(OC#N)cc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.38
ALDH1A1 P00352 4/20 0.36
ADORA1 P30542 5/20 0.34
ADORA2A P29274 4/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
HPGD P15428 3/20 0.33
ERBB2 P04626 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
MAOB P27338 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
ADORA2B P29275 1/20 0.31
KDM4E B2RXH2 2/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2404544 0.87 NAAA (0.46) NAAAALDH1A1ADORA1ADORA2ACA1
Methane SCHEMBL28184594 0.78 NAAA (0.40) NAAAALDH1A1CA1CA2CA9
Biphenyl SCHEMBL28306828 0.78 LTA4H (0.47) NAAACA1CA2CA9MAOB
Biphenyl SCHEMBL7925417 0.78 ALDH1A1 (0.53) ALDH1A1CA1CA2CA9CHRNB2
SCHEMBL184515 0.78 MMP2 (0.34) NAAAALDH1A1ADORA1HPGDSMN1; SMN2
Water SCHEMBL1155688 0.78 TSHR (0.45) ALDH1A1CA1CA2CA9SMN1; SMN2
SCHEMBL28281167 0.78 TSHR (0.45) ALDH1A1CA1CA2CA9SMN1; SMN2
Water SCHEMBL27739593 0.78 TSHR (0.45) ALDH1A1CA1CA2CA9SMN1; SMN2
SCHEMBL100094 0.78
SCHEMBL17042226 0.77 NAAA (0.39) NAAAALDH1A1ADORA1ADORA2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563756-A1 POLY(ALLYL ETHER)S OF POLYCYCLOPENTADIENE POLYPHENOL Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
WO-2011136847-A1 POLY(ALLYL ETHER)S OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed