SCHEMBL2404544

SCHEMBL2404544

N#COc1ccc(-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.46
ALDH1A1 P00352 3/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CYP1A2 P05177 3/20 0.39
MAPK1 P28482 1/20 0.39
CYP3A4 P08684 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
CYP2C19 P33261 1/20 0.38
ADORA1 P30542 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184515 0.90 MMP2 (0.34) NAAAALDH1A1MAPK1MMP3NPC1
Methane SCHEMBL28184594 0.90 NAAA (0.40) NAAAALDH1A1CA1CA2CA9
SCHEMBL17042226 0.88 NAAA (0.39) NAAAALDH1A1CA1CA2CA9
Biphenyl SCHEMBL2583908 0.87 NAAA (0.38) NAAAALDH1A1CA1CA2CA9
Methane SCHEMBL28013431 0.87 ABL1 (0.40) NAAAALDH1A1CYP1A2MAPK1HSD17B10
SCHEMBL3424396 0.87 NCOA1 (0.39) NAAAALDH1A1CA1CA2CA9
Biphenyl SCHEMBL28306828 0.86 LTA4H (0.47) NAAACA1CA2CA9TAAR1
SCHEMBL100094 0.85
Water SCHEMBL1155688 0.85 TSHR (0.45) ALDH1A1CA1CA2CA9CYP1A2
SCHEMBL28281167 0.85 TSHR (0.45) ALDH1A1CA1CA2CA9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115774-A1 HIGH PERFORMANCE THERMOSET RESINS FOR 3D PRINTING NOGA 3D INNOVATIONS LTD (IL) 2025-04-10 US claimed
EP-4466319-A1 HIGH PERFORMANCE THERMOSET RESINS FOR 3D PRINTING Noga 3D Innovations Ltd (IL) 2024-11-27 EP claimed
CN-118574903-A High performance thermosetting resins for 3D printing 诺佳3D创新有限公司 2024-08-30 CN claimed
WO-2023139579-A1 HIGH PERFORMANCE THERMOSET RESINS FOR 3D PRINTING NOGA 3D INNOVATIONS LTD (IL) 2023-07-27 WO claimed
EP-3344676-B1 CYANATE ESTER DUAL CURE RESINS FOR ADDITIVE MANUFACTURING CARBON INC (US) 2023-04-12 EP claimed
CN-108350145-B Cyanate ester dual cure resin for additive manufacturing 卡本有限公司 2021-06-22 CN claimed
US-10618892-B2 Processes for the preparation of a BACE inhibitor MERCK SHARP & DOHME CORP. (US) 2020-04-14 US claimed
US-20200039975-A1 PROCESSES FOR THE PREPARATION OF A BACE INHIBITOR MERCK SHARP & DOHME CORP. (US) 2020-02-06 US claimed
US-10471655-B2 Cyanate ester dual resins for additive manufacturing CARBON, INC. (US) 2019-11-12 US claimed
US-20190010343-A1 CYANATE ESTER DUAL RESINS FOR ADDITIVE MANUFACTURING CARBON3D INC (US) 2019-01-10 US claimed
EP-1979397-A4 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RES GROUP INC (US) 2009-04-08 EP claimed
EP-1979397-A2 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2008-10-15 EP claimed
WO-2008051241-A2 SHAPE MEMORY CYANATE ESTER COPOLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2008-05-02 WO claimed
US-7223861-B2 Process for preparing substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidines SCHERING CORPORATION (US) 2007-05-29 US claimed
JP-2007509948-A 2007-04-19 JP claimed
EP-1678182-B1 PROCESS FOR PREPARING SUBSTITUTED 5-AMINO-PYRAZOLO- [4,3-E]-1,2,4-TRIAZOLO [1,5-C]PYRIMIDINES SCHERING CORP (US) 2007-02-07 EP claimed
EP-1678182-A1 PROCESS FOR PREPARING SUBSTITUTED 5-AMINO-PYRAZOLO- [4,3-E]-1,2,4-TRIAZOLO [1,5-C]PYRIMIDINES Schering Corporation (US) 2006-07-12 EP claimed
WO-2005044819-A1 PROCESS FOR PREPARING SUBSTITUTED 5-AMINO-PYRAZOLO-[4,3-E]-1,2,4-TRIAZOLO[1,5-C]PYRIMIDINES SCHERING CORPORATION (US) 2005-05-19 WO claimed
US-20050090492-A1 Process for preparing substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine SCHERING CORPORATION 2005-04-28 US claimed
EP-0326931-A2 Thermosetting resin composition CYTEC TECHNOLOGY CORP. (US) 1989-08-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200039975-A1 PROCESSES FOR THE PREPARATION OF A BACE INHIBITOR BACE2, BACE1, APP NAAA 3019/4885ALDH1A1 837/4885CA1 399/4885
US-10618892-B2 Processes for the preparation of a BACE inhibitor BACE2, BACE1, APP NAAA 3019/4885ALDH1A1 837/4885CA1 399/4885
US-20050090492-A1 Process for preparing substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine TYMP, DCK, TK1 NAAA 1702/4885ALDH1A1 997/4885CA1 3913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.