Diphenylmethane

Diphenylmethane

SCHEMBL2583973

O=C=Nc1ccc(Oc2ccc(N=C=O)cc2)cc1.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.63
TSHR P16473 1/20 0.63
CYP1A2 P05177 1/20 0.47
SRD5A2 P31213 1/20 0.47
LTA4H P09960 3/20 0.43
CALM1 P0DP23 1/20 0.41
PPARG P37231 5/20 0.41
PPARA Q07869 5/20 0.41
SLC22A2 O15244 1/20 0.40
ACACB O00763 1/20 0.39
ACACA Q13085 1/20 0.39
HPGD P15428 1/20 0.38
NR3C1 P04150 1/20 0.38
IDH1 O75874 1/20 0.38
FFAR1 O14842 1/20 0.38
PGR P06401 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6009600 0.91 CYP3A4 (0.77) CYP3A4TSHRCYP1A2SRD5A2LTA4H
SCHEMBL510929 0.87 CYP3A4 (0.83) CYP3A4TSHRCYP1A2LTA4HCALM1
SCHEMBL242048 0.87 LTA4H (0.50) CYP3A4TSHRSRD5A2LTA4H
Diphenylmethane SCHEMBL4537622 0.87 CYP3A4 (0.83) CYP3A4TSHRCYP1A2LTA4HCALM1
SCHEMBL6940160 0.84 CYP3A4 (0.45) CYP3A4TSHRCYP1A2SRD5A2PPARG
Diphenylmethane SCHEMBL28882075 0.84 CYP3A4 (0.70) CYP3A4TSHRCYP1A2LTA4HCALM1
SCHEMBL50333 0.83 CYP3A4 (0.54) CYP3A4TSHRCYP1A2LTA4HHPGD
SCHEMBL4551613 0.83 CYP3A4 (0.54) CYP3A4TSHRCYP1A2LTA4HHPGD
SCHEMBL4544188 0.83 CYP3A4 (0.54) CYP3A4TSHRCYP1A2LTA4HHPGD
Diphenylether SCHEMBL28412262 0.80 LTA4H (0.46) CYP3A4TSHRSRD5A2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048493-B2 Method of forming piezoelectric resin film KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-11-01 US disclosed
US-20080008825-A1 Method of forming piezoelectric resin film KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-01-10 US disclosed