Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936469 | 0.88 | CYP3A4 (0.37) | CYP3A4TSHRKDM4EALDH1A1MEN1 | |
| Diphenylmethane SCHEMBL2583973 | 0.84 | CYP3A4 (0.63) | CYP3A4TSHRCYP1A2SRD5A2IDH1 | |
| SCHEMBL6941382 | 0.79 | KDM4E (0.40) | CYP3A4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6941385 | 0.79 | KDM4E (0.40) | CYP3A4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6938764 | 0.78 | POLB (0.50) | CYP1A2SRD5A2KDM4EALDH1A1HTT | |
| SCHEMBL6940624 | 0.77 | NCOA1 (0.42) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL6009600 | 0.76 | CYP3A4 (0.77) | CYP3A4TSHRCYP1A2SRD5A2IDH1 | |
| SCHEMBL242048 | 0.76 | LTA4H (0.50) | CYP3A4TSHRSRD5A2 | |
| SCHEMBL7136291 | 0.73 | FURIN (0.53) | CYP3A4TSHRCYP1A2ALDH1A1MEN1 | |
| Diphenylmethane SCHEMBL4537622 | 0.73 | CYP3A4 (0.83) | CYP3A4TSHRCYP1A2IDH1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995739-B9 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORP (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-0995739-B1 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORP (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6248857-B1 | LOW MOISTURE RESISTANCE, HEAT RESISTANCE AND A LOW DIELECTRIC CONSTANT | NITTO DENKO CORPORATION (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0995739-A1 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORPORATION (JP) | 2000-04-26 | — | — | EP | disclosed |