Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296233 | 0.82 | MAP3K12 (0.32) | KDM4EMBOAT4 | |
| SCHEMBL3449189 | 0.76 | MBOAT4 (0.36) | MBOAT4NOS3NOS2 | |
| SCHEMBL21279619 | 0.70 | KDM5B (0.36) | KDM4EKDM5BNOS3NOS2 | |
| SCHEMBL25840262 | 0.69 | KDM4E (0.54) | KDM4EPOLB | |
| SCHEMBL25256319 | 0.68 | ASPH (0.31) | — | |
| SCHEMBL8804672 | 0.67 | KIF11 (0.36) | POLB | |
| SCHEMBL16668061 | 0.67 | MAP3K12 (0.36) | KDM4EMBOAT4 | |
| SCHEMBL15412486 | 0.67 | NOS2 (0.39) | KDM4EMBOAT4POLBNOS2 | |
| SCHEMBL232921 | 0.66 | HEXA (0.43) | KDM4E | |
| SCHEMBL232036 | 0.66 | MBOAT4 (0.48) | KDM4EMBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125877-A1 | TRICYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |