Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627979 | 0.83 | CSNK1A1 (0.41) | PGK1CYP11B2CSNK1A1CLK4ALDH1A1 | |
| SCHEMBL21927208 | 0.80 | UHRF1 (0.38) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL4486546 | 0.78 | CYP11B2 (0.40) | PGK1CYP11B2CSNK1A1CLK4ALDH1A1 | |
| SCHEMBL2751008 | 0.78 | UHRF1 (0.41) | CYP11B2ALDH1A1NPSR1TDP1KDM4E | |
| SCHEMBL10959324 | 0.75 | TRPV4 (0.44) | PGK1CYP11B2CSNK1A1CLK4ALDH1A1 | |
| SCHEMBL4311935 | 0.75 | CYP11B2 (0.53) | PGK1CYP11B2CSNK1A1CLK4ALDH1A1 | |
| SCHEMBL12055453 | 0.75 | MBOAT4 (0.39) | CYP11B2KDM4EUHRF1CYP1A2CYP2A6 | |
| SCHEMBL19565921 | 0.75 | CYP11B2 (0.41) | CYP11B2TRPV4UHRF1CYP11B1 | |
| SCHEMBL29483790 | 0.75 | CYP11B2 (0.53) | PGK1CYP11B2CSNK1A1CLK4ALDH1A1 | |
| SCHEMBL10960323 | 0.75 | PGK1 (0.39) | PGK1CYP11B2CSNK1A1CLK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338429-A1 | COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS | UNIVERSITE DE MONTREAL (CA) | 2023-10-26 | — | — | US | disclosed |
| US-11696928-B2 | Compounds and use thereof in the expansion of stem cells and/or progenitor cells | UNIVERSITE DE MONTREAL (CA) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696928-B2 | Compounds and use thereof in the expansion of stem cells and/or progenitor cells | MCL1, CD47, BMI1 | PGK1 3158/4885CYP11B2 2395/4885CSNK1A1 3510/4885 |
| US-20230338429-A1 | COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS | MCL1, CD47, BMI1 | PGK1 3158/4885CYP11B2 2395/4885CSNK1A1 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.