Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286023 | 0.82 | CSNK1A1 (0.44) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL30445578 | 0.82 | CSNK1A1 (0.44) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL19565835 | 0.78 | ALDH1A1 (0.40) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL30931692 | 0.78 | KCNQ3 (0.44) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL15074083 | 0.78 | XDH (0.39) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL25234861 | 0.78 | CSNK1A1 (0.46) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL19517506 | 0.78 | GRM4 (0.41) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL4319117 | 0.78 | KCNQ3 (0.44) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL10958106 | 0.78 | TRPV4 (0.39) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 | |
| SCHEMBL4311935 | 0.78 | CYP11B2 (0.53) | CYP11B2CSNK1A1CLK4ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296309-B1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | UNIV GENT (BE) | 2019-08-07 | — | — | EP | disclosed |
| EP-3296309-A1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | Universiteit Gent (BE) | 2018-03-21 | — | — | EP | disclosed |
| EP-2877480-B1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | UNIV GENT (BE) | 2017-09-06 | — | — | EP | disclosed |
| US-9321796-B2 | Galactopyranosyl derivatives useful as medicaments | UNIVERSITEIT GENT (BE) | 2016-04-26 | — | — | US | disclosed |
| US-20150210728-A1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | AMBICION CO., LTD. (JP) | 2015-07-30 | — | — | US | disclosed |
| EP-2877480-A1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | Universiteit van Gent (BE) | 2015-06-03 | — | — | EP | disclosed |
| WO-2014001204-A1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | UNIVERSITEIT GENT (BE) | 2014-01-03 | — | — | WO | disclosed |
| US-7601714-B2 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601714-B2 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601714-B2 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20060025433-A1 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-02-02 | — | — | US | disclosed |
| US-20040077681-A1 | Pyrazolo[3,4-c]pyridines as gsk-3 inhibitors | SMITHKLINE BEECHAM P.L.C (GB) | 2004-04-22 | — | — | US | disclosed |
| EP-1347972-A1 | PYRAZOLO 3,4-C]PYRIDINES AS GSK-3 INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002050073-A1 | PYRAZOLO[3,4-C]PYRIDINES AS GSK-3 INHIBITORS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-27 | — | — | WO | disclosed |
| EP-0822930-B1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5763463-A | Pyridine compounds which are useful as pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0822930-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033975-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |
| US-4558040-A | Miticidal (2-alkyl-3,4-dihydro-2H-1-benzopyran-8-yl)-diazenecarboxylic acid esters | SHELL OIL COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4558134-A | PICORNAVIRUS | THE DOW CHEMICAL COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077681-A1 | Pyrazolo[3,4-c]pyridines as gsk-3 inhibitors | GSK3B, GSK3A, GSKIP | CYP11B2 652/4885CSNK1A1 40/4885CLK4 599/4885 |
| US-20060025433-A1 | Pyrimidine derivatives useful as inhibitors of PKC-theta | PRKCZ, PRKCQ, PRKCH | CYP11B2 610/4885CSNK1A1 132/4885CLK4 2180/4885 |
| US-20150210728-A1 | GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS | B3GAT3, GALR3, ST6GAL1 | CYP11B2 2071/4885CSNK1A1 300/4885CLK4 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.