SCHEMBL25842242

SCHEMBL25842242

Cc1cccc2c(CC(C)C(=O)O)c[nH]c12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS2 Q07890 1/20 0.65
MAPT P10636 4/20 0.63
POLB P06746 3/20 0.63
KDM4E B2RXH2 2/20 0.63
APAF1 O14727 1/20 0.63
RECQL P46063 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
HTR2A P28223 1/20 0.52
NR3C1 P04150 2/20 0.52
SMN1; SMN2 Q16637 3/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ITGB2 P05107 2/20 0.50
ICAM1 P05362 2/20 0.50
ITGAL P20701 2/20 0.50
BRPF1 P55201 1/20 0.50
NR4A2 P43354 1/20 0.47
PGR P06401 1/20 0.46
NR3C2 P08235 1/20 0.46
TRIM24 O15164 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12039401 1.00 SOS2 (0.65) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL24328921 0.86 SMN1; SMN2 (0.61) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL28417401 0.86 SMN1; SMN2 (0.61) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL29405720 0.84 SOS2 (0.68) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL10023253 0.84 SOS2 (0.68) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL31369774 0.84 SOS2 (0.68) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL2033277 0.84 SOS2 (0.68) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL2033276 0.84 SOS2 (0.68) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL24328895 0.83 SOS2 (0.58) SOS2MAPTPOLBKDM4EAPAF1
SCHEMBL30955892 0.82 ITGB2 (0.59) SOS2MAPTPOLBHTR2ANR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219888-A1 PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2023-07-13 US disclosed
US-20110319274-A1 Identification of Compounds Modifying a Cellular Response CARLSBERG A/S (DK) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219888-A1 PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING AANAT, ACAT2, PCYT1A SOS2 3327/4885MAPT 2331/4885POLB 1233/4885
US-20110319274-A1 Identification of Compounds Modifying a Cellular Response MYD88, CD14, STAT1 SOS2 1449/4885MAPT 4625/4885POLB 4536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.