SCHEMBL2584541

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2463127	0.88	PTGS2 (0.39)	MTNR1AMTNR1BALDH1A1MAPTKDM4E
	SCHEMBL2584544	0.88	NEK1 (0.34)	MTNR1AMTNR1BCNR1
	SCHEMBL2585468	0.86	PDE3B (0.36)	MTNR1AMTNR1BALDH1A1MAPTSMN1; SMN2
	SCHEMBL2492254	0.82	MAOB (0.37)	MTNR1AMTNR1B
	SCHEMBL1136308	0.81	MAOB (0.39)	MAPTHPGDL3MBTL1
	SCHEMBL2578819	0.80	PDE4A (0.42)	MTNR1AMTNR1BALDH1A1MAPTSMN1; SMN2
	SCHEMBL2581569	0.80	KDM4E (0.34)	MTNR1AMTNR1BSMN1; SMN2KDM4E
	SCHEMBL2588854	0.79	MAOB (0.33)	MTNR1AMTNR1BSMN1; SMN2KDM4E
	SCHEMBL2462830	0.78	PTGS2 (0.38)	MTNR1AMTNR1BALDH1A1SMN1; SMN2PDE4D
	SCHEMBL2588809	0.77	ACR (0.39)	MTNR1AMTNR1BSMN1; SMN2PDE4DKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.