Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | VDR | P11473 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25846208 | 1.00 | ESR1 (0.35) | ESR1ESR2VDRKDM4EMEN1 | |
| SCHEMBL25846210 | 0.83 | ESR1 (0.37) | ESR1ESR2VDRKLF10ACE2 | |
| SCHEMBL25846204 | 0.81 | SLC6A2 (0.47) | ESR1VDRKDM4EMEN1USP2 | |
| SCHEMBL25751730 | 0.77 | ESR1 (0.48) | ESR1ESR2VDRKDM4EMEN1 | |
| SCHEMBL9161555 | 0.77 | ALOX15 (0.57) | ESR1KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL25846211 | 0.74 | CYP3A4 (0.46) | VDRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL25846222 | 0.74 | CYP1A2 (0.62) | VDRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL10492288 | 0.72 | TAAR1 (0.49) | ALDH1A1CYP1A2CYP3A4GAAMAPT | |
| SCHEMBL18801247 | 0.72 | ESR1 (0.41) | ESR1ESR2KDM4EMEN1USP2 | |
| SCHEMBL24534352 | 0.71 | CA2 (0.50) | KDM4EMEN1USP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702383-B2 | Methods for producing D-α-methyldopa | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702383-B2 | Methods for producing D-α-methyldopa | AMPD2, AMPD3, AMPD1 | ESR1 3494/4885ESR2 2322/4885VDR 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.