Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR0B1 | P51843 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.79 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.46 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.46 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cytochalasin D SCHEMBL33528 | 1.00 | NR0B1 (1.00) | NR0B1ADORA3CCR5MEN1KMT2A | |
| Cytochalasin D SCHEMBL16502284 | 1.00 | NR0B1 (1.00) | NR0B1ADORA3CCR5MEN1KMT2A | |
| Cytochalasin D SCHEMBL33529 | 1.00 | NR0B1 (1.00) | NR0B1ADORA3CCR5MEN1KMT2A | |
| Cytochalasin D SCHEMBL31734099 | 1.00 | NR0B1 (1.00) | NR0B1ADORA3CCR5MEN1KMT2A | |
| Cytochalasin D SCHEMBL29375699 | 1.00 | NR0B1 (1.00) | NR0B1ADORA3CCR5MEN1KMT2A | |
| Cytochalasin D SCHEMBL12648577 | 1.00 | NR0B1 (1.00) | NR0B1ADORA3CCR5MEN1KMT2A | |
| SCHEMBL29745878 | 0.93 | NR0B1 (0.86) | NR0B1ADORA3CCR5MEN1KMT2A | |
| Zygosporin D SCHEMBL34014 | 0.89 | NR0B1 (0.80) | NR0B1ADORA3CCR5MEN1KMT2A | |
| SCHEMBL22621306 | 0.88 | NR0B1 (0.79) | NR0B1ADORA3CCR5MEN1KMT2A | |
| SCHEMBL33708 | 0.88 | ADORA3 (1.00) | NR0B1ADORA3CCR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708391-B2 | Rapaglutins, novel inhibitors of GLUT and use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708391-B2 | Rapaglutins, novel inhibitors of GLUT and use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708391-B2 | Rapaglutins, novel inhibitors of GLUT and use thereof | SLC2A1, SLC2A4, SLC2A2 | NR0B1 423/4885ADORA3 3756/4885CCR5 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.