Cytochalasin D

Cytochalasin D

SCHEMBL33528

C=C1C(C)C2C(Cc3ccccc3)NC(=O)C23C(OC(C)=O)/C=C/C(C)(O)C(=O)C(C)C/C=C\C3C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR0B1 P51843 1/20 1.00
ADORA3 P0DMS8 1/20 0.79
CCR5 P51681 1/20 0.52
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NPC1 O15118 2/20 0.46
LMNA P02545 1/20 0.46
SLC2A1 P11166 1/20 0.46
SLC2A2 P11168 1/20 0.46
SLC2A3 P11169 1/20 0.46
SLC2A4 P14672 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46
SLC2A9 Q9NRM0 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
PAX8 Q06710 1/20 0.46
ABCB1 P08183 8/20 0.33
CYP3A4 P08684 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytochalasin D SCHEMBL16502284 1.00 NR0B1 (1.00) NR0B1ADORA3CCR5MEN1KMT2A
Cytochalasin D SCHEMBL33529 1.00 NR0B1 (1.00) NR0B1ADORA3CCR5MEN1KMT2A
Cytochalasin D SCHEMBL31734099 1.00 NR0B1 (1.00) NR0B1ADORA3CCR5MEN1KMT2A
Cytochalasin D SCHEMBL29375699 1.00 NR0B1 (1.00) NR0B1ADORA3CCR5MEN1KMT2A
Cytochalasin D SCHEMBL25847004 1.00 NR0B1 (1.00) NR0B1ADORA3CCR5MEN1KMT2A
Cytochalasin D SCHEMBL12648577 1.00 NR0B1 (1.00) NR0B1ADORA3CCR5MEN1KMT2A
SCHEMBL29745878 0.93 NR0B1 (0.86) NR0B1ADORA3CCR5MEN1KMT2A
Zygosporin D SCHEMBL34014 0.89 NR0B1 (0.80) NR0B1ADORA3CCR5MEN1KMT2A
SCHEMBL22621306 0.88 NR0B1 (0.79) NR0B1ADORA3CCR5MEN1KMT2A
SCHEMBL33708 0.88 ADORA3 (1.00) NR0B1ADORA3CCR5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5303 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333993-B Construction method of aneuploid ovarian cancer cell model 复旦大学附属妇产科医院 2026-05-19 CN claimed
EP-4735884-A1 METHOD OF SCREENING COMPOUNDS FOR ASSESSING ENDOCYTIC ACTIVITY IN THE CONTEXT OF NEURODEGENERATIVE DISORDERS National Centre For Cell Science (IN) 2026-05-06 EP claimed
EP-3411059-B1 METHOD TO ENHANCE THE EFFICIENCY OF SYSTEMIC AAV GENE DELIVERY TO THE CENTRAL NERVOUS SYSTEM UNIV MASSACHUSETTS (US) 2026-05-06 EP claimed
EP-4058037-B1 FIBROBLAST-BASED THERAPY FOR TREATMENT AND PREVENTION OF STROKE SPINALCYTE LLC (US) 2026-01-28 EP claimed
EP-3350313-B1 DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) 2025-11-26 EP claimed
EP-4642933-A1 COMPOSITIONS, KITS AND METHODS FOR DETERMINING PERSONALIZED TREATMENT REGIMEN Ramot at Tel-Aviv University Ltd. (IL) 2025-11-05 EP claimed
US-12399187-B2 Controlled blood delivery to mixing chamber of a blood testing cartridge CA CASYSO GMBH (CH) 2025-08-26 US claimed
US-20250223564-A1 HYPOIMMUNE BETA CELLS DIFFERENTIATED FROM PLURIPOTENT STEM CELLS AND RELATED USES AND METHODS SANA BIOTECHNOLOGY, INC. 2025-07-10 US claimed
WO-2025109524-A1 ASSAYS AND METHODS FOR ASSESSING VACCINE PREPARATIONS AC IMMUNE SA (CH) 2025-05-30 WO claimed
EP-3734274-B1 SYSTEM FOR MEASURING VISCOELASTIC PROPERTIES OF BLOOD C A CASYSO GMBH (CH) 2025-04-23 EP claimed
EP-0684762-A1 PRESERVATION OF BLOOD PLATELETS BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 1995-12-06 EP claimed
EP-0681475-A1 THERAPEUTIC INHIBITORS OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1995-11-15 EP claimed
US-5358844-A Treating platelets with agent for inhibiting actin filament severing and another for inhibiting actin addition reactions, then low temperature storage preserves hemostatic activity BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 1994-10-25 US claimed
EP-0616530-A1 USE OF CYTOCHALASINS FOR INHIBITING VIRAL REPLICATION Usher, Thomas Clemens (BS) 1994-09-28 EP claimed
WO-1994018829-A1 PRESERVATION OF BLOOD PLATELETS BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 1994-09-01 WO claimed
WO-1994016706-A1 THERAPEUTIC INHIBITORS OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1994-08-04 WO claimed
WO-1993011763-A1 USE OF CYTOCHALASINS FOR INHIBITING VIRAL REPLICATION USHER THOMAS C (BS) 1993-06-24 WO claimed
EP-0429585-A4 CYTOCHALASIN COMPOSITIONS AND THERAPEUTIC METHODS 1992-03-25 EP claimed
EP-0429585-A1 CYTOCHALASIN COMPOSITIONS AND THERAPEUTIC METHODS SYRACUSE UNIVERSITY (US) 1991-06-05 EP claimed
WO-1990013293-A1 CYTOCHALASIN COMPOSITIONS AND THERAPEUTIC METHODS SYRACUSE UNIVERSITY (US) 1990-11-15 WO claimed