Zygosporin D

Zygosporin D

SCHEMBL34014

C=C1[C@@H](C)[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@]23[C@H](O)/C=C/[C@@](C)(O)C(=O)[C@@H](C)C/C=C/[C@H]3[C@@H]1O

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR0B1 P51843 1/20 0.80
ADORA3 P0DMS8 1/20 0.62
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
NPC1 O15118 2/20 0.51
LMNA P02545 1/20 0.51
SLC2A1 P11166 1/20 0.51
SLC2A2 P11168 1/20 0.51
SLC2A3 P11169 1/20 0.51
SLC2A4 P14672 1/20 0.51
MAPK1 P28482 1/20 0.51
RAB9A P51151 1/20 0.51
SLC2A9 Q9NRM0 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HIF1A Q16665 1/20 0.51
PAX8 Q06710 1/20 0.51
CCR5 P51681 1/20 0.46
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31734123 0.92 NR0B1 (0.78) NR0B1ADORA3MEN1KMT2ANPC1
Cytochalasin D SCHEMBL25847004 0.89 NR0B1 (1.00) NR0B1ADORA3MEN1KMT2ANPC1
Cytochalasin D SCHEMBL33529 0.89 NR0B1 (1.00) NR0B1ADORA3MEN1KMT2ANPC1
Cytochalasin D SCHEMBL29375699 0.89 NR0B1 (1.00) NR0B1ADORA3MEN1KMT2ANPC1
Cytochalasin D SCHEMBL33528 0.89 NR0B1 (1.00) NR0B1ADORA3MEN1KMT2ANPC1
Cytochalasin D SCHEMBL12648577 0.89 NR0B1 (1.00) NR0B1ADORA3MEN1KMT2ANPC1
Cytochalasin D SCHEMBL31734099 0.89 NR0B1 (1.00) NR0B1ADORA3MEN1KMT2ANPC1
Cytochalasin D SCHEMBL16502284 0.89 NR0B1 (1.00) NR0B1ADORA3MEN1KMT2ANPC1
SCHEMBL33772 0.87 ADORA3 (0.80) NR0B1ADORA3MEN1KMT2ANPC1
SCHEMBL29745878 0.81 NR0B1 (0.86) NR0B1ADORA3MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090062904-A1 STENT COATING ICON INTERVENTIONAL SYSTEMS, INC. 2009-03-05 US claimed
US-20260070124-A1 METHOD FOR FORMING A TUBE MIRUS LLC (US) 2026-03-12 US disclosed
EP-4404878-A1 COATING FOR REFRACTORY METAL ALLOY MiRus LLC (US) 2024-07-31 EP disclosed
EP-1858440-B1 IMPROVED METAL ALLOYS FOR MEDICAL DEVICE MIRUS LLC (US) 2024-04-24 EP disclosed
US-20240024542-A1 METAL ALLOYS FOR METAL DEVICES MIRUS LLC 2024-01-25 US disclosed
US-20230390454-A1 STENT DEVICE FOR SPINAL FUSION MIRUS LLC 2023-12-07 US disclosed
US-11779685-B2 Metal alloys for medical devices MIRUS LLC (US) 2023-10-10 US disclosed
US-11766506-B2 Stent device for spinal fusion MIRUS LLC (US) 2023-09-26 US disclosed
EP-3316826-B1 MOLYBDENUM ALLOYS FOR MEDICAL DEVICES MIRUS LLC (US) 2023-04-19 EP disclosed
WO-2023048840-A1 COATING FOR REFRACTORY METAL ALLOY MIRUS LLC (US) 2023-03-30 WO disclosed
WO-1998043618-A2 USE OF CYTOSKELETAL INHIBITORS FOR THE PREVENTION OF RESTENOSIS NEORX CORPORATION (US) 1998-10-08 WO disclosed
US-5811447-A Therapeutic inhibitor of vascular smooth muscle cells NEORX CORPORATION (US) 1998-09-22 US disclosed
EP-0702557-A4 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORP (US) 1998-06-03 EP disclosed
US-5733925-A ADMINISTERING TAXOL TREATING CARDIOVASCULAR DISORDER NEORX CORPORATION (US) 1998-03-31 US disclosed
EP-0809515-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1997-12-03 EP disclosed
WO-1996025176-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1996-08-22 WO disclosed
EP-0702557-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1996-03-27 EP disclosed
EP-0681475-A1 THERAPEUTIC INHIBITORS OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1995-11-15 EP disclosed
WO-1994026291-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1994-11-24 WO disclosed
WO-1994016706-A1 THERAPEUTIC INHIBITORS OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1994-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070124-A1 METHOD FOR FORMING A TUBE NIT2, NFE2L2, DUOX2 NR0B1 2547/4885ADORA3 3123/4885MEN1 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.