Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19432166 | 0.78 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL23762614 | 0.76 | LRRK2 (0.33) | LRRK2 | |
| SCHEMBL22509122 | 0.72 | ALOX15 (0.33) | ALOX15 | |
| SCHEMBL21626242 | 0.70 | NLRP3 (0.31) | — | |
| SCHEMBL13684190 | 0.67 | — | — | |
| SCHEMBL24439537 | 0.67 | TP53 (0.38) | — | |
| SCHEMBL15528452 | 0.65 | LRRK2 (0.36) | ALOX15LRRK2 | |
| SCHEMBL21646741 | 0.64 | — | — | |
| SCHEMBL20861635 | 0.64 | CYP11B1 (0.43) | CYP11B1CYP11B2LRRK2 | |
| SCHEMBL19880654 | 0.63 | ALOX15 (0.35) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702428-B2 | Chemical compounds as inhibitors of interleukin-1 activity | GENENTECH, INC. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702428-B2 | Chemical compounds as inhibitors of interleukin-1 activity | IL1B, IL1A, IL18 | ALOX15 779/4885CYP11B1 2628/4885CYP11B2 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.