Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24221428 | 0.77 | CYP1A2 (0.46) | ALDH1A1CYP3A4CYP2D6PSEN1PSEN2 | |
| SCHEMBL22618921 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL11511836 | 0.71 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2VCAM1CYP2C9CA1 | |
| SCHEMBL25847433 | 0.70 | NOS3 (0.44) | ALDH1A1SMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL13181463 | 0.69 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2VCAM1CYP2C9CA1 | |
| SCHEMBL3055959 | 0.69 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2VCAM1CYP2C9CA1 | |
| SCHEMBL22031407 | 0.68 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL12181468 | 0.67 | ALDH1A1 (0.68) | ALDH1A1CYP2C9CA2MEN1KMT2A | |
| SCHEMBL7030147 | 0.67 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2VCAM1CYP2C9CA1 | |
| SCHEMBL350324 | 0.67 | KMT2A (0.77) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | ALDH1A1 3871/4885SMN1; SMN2 2169/4885VCAM1 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.