Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180198 | 0.79 | NOS3 (0.50) | NOS3NOS1NOS2PKMALDH1A1 | |
| SCHEMBL21422570 | 0.77 | NOS3 (0.53) | NOS3NOS1NOS2PKMALDH1A1 | |
| SCHEMBL8431657 | 0.77 | NOS3 (0.48) | NOS3NOS1NOS2PKMALDH1A1 | |
| SCHEMBL31527882 | 0.76 | NOS3 (0.52) | NOS3NOS1NOS2PKMKDM4E | |
| SCHEMBL18881310 | 0.74 | L3MBTL1 (0.65) | PKMALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL25847430 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP2C9 | |
| SCHEMBL4637636 | 0.70 | LOXL2 (0.45) | LMNAHTTSMN1; SMN2NR2F2 | |
| SCHEMBL13181463 | 0.69 | ALDH1A1 (0.55) | ALDH1A1KMT2ASMN1; SMN2CYP2C9BRD4 | |
| SCHEMBL26078700 | 0.69 | NOS3 (0.40) | NOS3NOS1NOS2PKMKDM4E | |
| SCHEMBL25847426 | 0.68 | KDM4E (0.51) | NOS3NOS1NOS2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | NOS3 817/4885NOS1 3333/4885NOS2 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.