Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541402 | 0.79 | TDP1 (0.47) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 | |
| SCHEMBL2095103 | 0.79 | HSD17B1 (0.46) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 | |
| SCHEMBL14883479 | 0.78 | HSD17B1 (0.45) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 | |
| SCHEMBL24406106 | 0.76 | HSD17B1 (0.44) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 | |
| SCHEMBL12879 | 0.75 | ALDH1A1 (0.56) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 | |
| SCHEMBL1697445 | 0.75 | ACHE (0.55) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 | |
| SCHEMBL1740936 | 0.75 | MEN1 (0.42) | TDP1MAPK1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29381010 | 0.75 | ALDH1A1 (0.56) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 | |
| SCHEMBL16994795 | 0.73 | HSD17B1 (0.42) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 | |
| SCHEMBL21065746 | 0.73 | ALDH1A1 (0.54) | ACHEHSD17B1HSD17B2SIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143645-A | Industrial method for synthesizing tolnaftate by one-pot method | 内蒙古幸源新材料科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-104341330-A | N-methyl-N-(3-methyl phenyl) thioformamide and application thereof | SICHUAN MOER BIOLOG PHARMACEUTICAL CO LTD | 2015-02-11 | — | — | CN | disclosed |
| CN-104341330-A | N-methyl-N-(3-methyl phenyl) thioformamide and application thereof | SICHUAN MOER BIOLOG PHARMACEUTICAL CO LTD | 2015-02-11 | — | — | CN | disclosed |
| US-20130231334-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-05 | — | — | US | disclosed |
| EP-2563118-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS | Syngenta Participations AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134819-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231334-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS | DDT, AGO2, INF2 | ACHE 791/4885HSD17B1 2949/4885HSD17B2 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.