SCHEMBL25848473

SCHEMBL25848473

CCCCCCCCCCCCCCCC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CC(C)(C)COCC(C)(C)CNC(=O)CC[C@H](N)C(=O)NCC(C)(C)COCC(C)(C)CC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 7/20 0.40
RRM1 P23921 1/20 0.40
DPP7 Q9UHL4 2/20 0.39
GNAI3 P08754 1/20 0.38
GNAO1 P09471 1/20 0.38
GNAI1 P63096 1/20 0.38
FAAH O00519 4/20 0.38
TLR2 O60603 2/20 0.36
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27384250 0.86 TLR2 (0.38) NOD1RRM1DPP7GNAI3GNAO1
SCHEMBL24340790 0.86 NOD1 (0.36) NOD1FAAHCYP1A2CYP3A4CYP2C19
SCHEMBL25850206 0.83 FAAH (0.43) FAAHTLR2
SCHEMBL25842691 0.82 DPP7 (0.34) NOD1RRM1DPP7GNAI3GNAO1
SCHEMBL24341855 0.82 FAAH (0.44) FAAH
SCHEMBL21096814 0.80 FAAH (0.46) FAAH
SCHEMBL25842349 0.79
SCHEMBL26034080 0.78 FAAH (0.47) FAAHTLR2
SCHEMBL25843022 0.77 BCHE (0.41) NOD1CYP1A2CYP2C19
SCHEMBL25849437 0.76 FAAH (0.43) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 NOD1 4881/4885RRM1 128/4885DPP7 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.