SCHEMBL25849437

SCHEMBL25849437

CCCCCCCCCCCCCCCC(=O)NCC(C)(C)COCC(C)(C)CC(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.43
GAA P10253 1/20 0.39
DNM1 Q05193 2/20 0.38
HSP90AA1 P07900 1/20 0.37
CNR1 P21554 3/20 0.36
CNR2 P34972 3/20 0.36
RECQL P46063 1/20 0.36
CASP2 P42575 1/20 0.36
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24340612 0.93 FAAH (0.39) FAAHGAADNM1HSP90AA1CNR1
SCHEMBL21096814 0.85 FAAH (0.46) FAAHGAADNM1HSP90AA1CNR1
SCHEMBL23482831 0.84 MEN1 (0.32)
SCHEMBL24341855 0.83 FAAH (0.44) FAAHDNM1CNR1CNR2CASP2
SCHEMBL25850206 0.82 FAAH (0.43) FAAHGAADNM1HSP90AA1CNR1
SCHEMBL24340786 0.82 FAAH (0.31) FAAHDNM1
SCHEMBL26034080 0.81 FAAH (0.47) FAAHGAADNM1HSP90AA1CNR1
SCHEMBL24341652 0.80 FAAH (0.37) FAAHGAA
SCHEMBL25850207 0.79 DNM1 (0.34) FAAHDNM1CNR1CNR2
SCHEMBL11245690 0.78 FAAH (0.50) FAAHGAADNM1HSP90AA1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 FAAH 2901/4885GAA 201/4885DNM1 376/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 FAAH 4742/4885GAA 438/4885DNM1 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.