SCHEMBL25850206

SCHEMBL25850206

CCCCCCCCCCCCCCCC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CC(C)(C)COCC(C)(C)CN

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.43
SLC6A5 Q9Y345 2/20 0.39
DNM1 Q05193 3/20 0.38
HSP90AA1 P07900 1/20 0.37
STS P08842 3/20 0.37
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
GAA P10253 1/20 0.36
TLR2 O60603 1/20 0.36
CASP2 P42575 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26034080 0.95 FAAH (0.47) FAAHSLC6A5DNM1HSP90AA1CNR1
SCHEMBL24341855 0.88 FAAH (0.44) FAAHDNM1CNR1CNR2CASP2
SCHEMBL21096814 0.85 FAAH (0.46) FAAHDNM1HSP90AA1CNR1CNR2
SCHEMBL25848473 0.83 NOD1 (0.40) FAAHTLR2
SCHEMBL25839728 0.82 CASP2 (0.44) FAAHSLC6A5CASP2
SCHEMBL25849437 0.82 FAAH (0.43) FAAHDNM1HSP90AA1CNR1CNR2
SCHEMBL27817907 0.82 FAAH (0.53) FAAHSLC6A5DNM1HSP90AA1CASP2
SCHEMBL25840004 0.81 KDM4E (0.33)
SCHEMBL26035258 0.79 CNR1 (0.38) FAAHCNR1CNR2
SCHEMBL24340761 0.79 FAAH (0.51) FAAHSLC6A5DNM1HSP90AA1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 FAAH 2901/4885SLC6A5 4323/4885DNM1 376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.