SCHEMBL25848619

SCHEMBL25848619

CC(C)c1cc(C(C)C)n2nc(C(C)C)cc2c1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
FABP3 P05413 1/20 0.31
FABP4 P15090 1/20 0.31
PDE4B Q07343 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27017051 0.73 PDE4B (0.32) ALDH1A1GAAPDE4B
SCHEMBL24371169 0.72 HTR4 (0.42) ALDH1A1GAAPDE4B
SCHEMBL25848617 0.69 NOS3 (0.35) ALDH1A1
SCHEMBL25848614 0.68 HAVCR2 (0.33)
SCHEMBL25848612 0.67 FABP3 (0.32) FABP3FABP4
SCHEMBL13086417 0.67 HTR4 (0.31)
SCHEMBL798520 0.67 ALDH1A1 (0.33) ALDH1A1GAA
SCHEMBL27112031 0.64 PDE4B (0.33) ALDH1A1GAAPDE4B
SCHEMBL25848618 0.64 NOS3 (0.32)
SCHEMBL27112088 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708369-B2 Heteroaromatic compounds having activity against RSV Janssen Sciences Ireland Unlimited Company (IE) 2023-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708369-B2 Heteroaromatic compounds having activity against RSV MAVS, ZC3HAV1, SARS1 ALDH1A1 1873/4885GAA 548/4885FABP3 3356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.