SCHEMBL25849144

SCHEMBL25849144

COc1ccc(C(O[C@@H]2C3OC(C4C(=O)N(CCC(=O)O)C(=O)C43)[C@@H]2OC(C)=O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
MAPT P10636 4/20 0.36
POLB P06746 1/20 0.36
SLC6A1 P30531 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC6A11 P48066 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.34
CYP2J2 P51589 1/20 0.34
MAPK1 P28482 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
TYMP P19971 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849146 0.93 EP300 (0.36) ALDH1A1SLC6A1KMT2ASLC6A11CYP2J2
SCHEMBL25849145 0.93 EP300 (0.36) ALDH1A1SLC6A1KMT2ASLC6A11CYP2J2
SCHEMBL6801773 0.91 PDPK1 (0.36) ALDH1A1MAPTSLC6A1KMT2ASLC6A11
SCHEMBL6791347 0.90 SLC6A1 (0.35) ALDH1A1MAPTSLC6A1KMT2ALMNA
SCHEMBL6796641 0.83 TYMP (0.35) ALDH1A1MAPTSLC6A1KMT2ALMNA
SCHEMBL23996822 0.81 MAPT (0.36) ALDH1A1MAPTPOLBSLC6A1KMT2A
SCHEMBL25849147 0.79 ALDH1A1 (0.38) ALDH1A1POLBLMNASMN1; SMN2CYP3A4
SCHEMBL25849142 0.79 CNR2 (0.37) POLBSLC6A1L3MBTL1SLC6A11SMN1; SMN2
SCHEMBL6797097 0.79 EDNRA (0.40) ALDH1A1SLC6A1KMT2ALMNASLC6A11
SCHEMBL6797102 0.79 EDNRA (0.40) ALDH1A1SLC6A1KMT2ALMNASLC6A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203474-A1 COMPOUND, SOLID CARRIER INCLUDING THE SAME AND METHOD FOR PREPARING NUCLEIC ACID INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed
US-20230203474-A1 COMPOUND, SOLID CARRIER INCLUDING THE SAME AND METHOD FOR PREPARING NUCLEIC ACID INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203474-A1 COMPOUND, SOLID CARRIER INCLUDING THE SAME AND METHOD FOR PREPARING NUCLEIC ACID SNRPA, NSUN2, POLRMT ALDH1A1 2601/4885MAPT 3002/4885POLB 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.