Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 5/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797097 | 0.86 | EDNRA (0.40) | SMN1; SMN2CYP2D6LMNAMAPK1HIF1A | |
| SCHEMBL6797102 | 0.86 | EDNRA (0.40) | SMN1; SMN2CYP2D6LMNAMAPK1HIF1A | |
| SCHEMBL6791347 | 0.85 | SLC6A1 (0.35) | TYMPSMN1; SMN2CYP2D6LMNAMAPK1 | |
| SCHEMBL6801773 | 0.84 | PDPK1 (0.36) | TYMPSMN1; SMN2ALDH1A1KMT2AKIF11 | |
| SCHEMBL25849144 | 0.83 | ALDH1A1 (0.36) | TYMPSMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL25849145 | 0.80 | EP300 (0.36) | CYP2D6MAPK1MEN1ALDH1A1CYP2C9 | |
| SCHEMBL25849146 | 0.80 | EP300 (0.36) | CYP2D6MAPK1MEN1ALDH1A1CYP2C9 | |
| SCHEMBL23996822 | 0.74 | MAPT (0.36) | TYMPLMNAMAPK1MEN1ALDH1A1 | |
| SCHEMBL18356894 | 0.74 | MAPT (0.36) | TYMPLMNAMAPK1MEN1ALDH1A1 | |
| SCHEMBL30823423 | 0.74 | KIF11 (0.37) | MAPK1MEN1KMT2AKIF11SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152905-A1 | Universal building blocks and support media for synthesis of oligonucleotides and their analogs | ISIS PHARMACEUTICALS, INC. | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152905-A1 | Universal building blocks and support media for synthesis of oligonucleotides and their analogs | POLM, POLRMT, POLB | TYMP 78/4885SMN1; SMN2 1805/4885CYP2D6 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.