Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.40 |
| ▸ | EDNRB | P24530 | 2/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797102 | 1.00 | EDNRA (0.40) | EDNRAEDNRBSLC6A1SLC6A11PTPN1 | |
| SCHEMBL6731702 | 0.86 | EDNRA (0.41) | EDNRAEDNRBSLC6A1SLC6A11KIF11 | |
| SCHEMBL6731698 | 0.86 | EDNRA (0.41) | EDNRAEDNRBSLC6A1SLC6A11KIF11 | |
| SCHEMBL6796641 | 0.86 | TYMP (0.35) | SLC6A1SLC6A11PTPN1KIF11MEN1 | |
| SCHEMBL6791347 | 0.81 | SLC6A1 (0.35) | SLC6A1SLC6A11PTPN1KIF11MEN1 | |
| SCHEMBL6801773 | 0.81 | PDPK1 (0.36) | SLC6A1SLC6A11PTPN1KIF11KMT2A | |
| SCHEMBL25849144 | 0.79 | ALDH1A1 (0.36) | SLC6A1SLC6A11KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6794788 | 0.77 | SLC6A11 (0.35) | SLC6A1SLC6A11PTPN1KIF11MEN1 | |
| SCHEMBL6795667 | 0.77 | SLC6A11 (0.35) | SLC6A1SLC6A11PTPN1KIF11MEN1 | |
| SCHEMBL25849145 | 0.77 | EP300 (0.36) | SLC6A1SLC6A11MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152905-A1 | Universal building blocks and support media for synthesis of oligonucleotides and their analogs | ISIS PHARMACEUTICALS, INC. | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152905-A1 | Universal building blocks and support media for synthesis of oligonucleotides and their analogs | POLM, POLRMT, POLB | EDNRA 3522/4885EDNRB 2108/4885SLC6A1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.